Evaluation of acute and subacute toxicity of the extract of allium cepa peels in Wistar rats

Allium cepa is a popular recipe used traditionally to treat diabetes, cardiovascular diseases, cancer, wounds and infections. The acute sub-acute oral toxicity profile of the aqueous extract peels were evaluated in wistar albino rats order determine its safety for use traditional medicine. median lethal dose (LD 50) body weights food intake determined. peel was carried out accordance with OECD guideline 423. In addition this, haematological parameters biochemical also evaluated. greater than 2000 mg/kg when given orally rats. There no significant changes level parameters. results from this study indicates that are relatively safe, hence supporting